Research article & Conference presentations:

1. Emanuel Vamanu, Diana Pelinescu, Irina Marin, Adrian Vamanu, Study of probiotic strains viability from PROBAC product in a single chamber gastrointestinal tract simulator, Food Science and Biotechnology – Springer, vol. 21, issue 4, pp. 979-985, 2012, impact factor 0.695.

2. Emanuel Vamanu, Diana Pelinescu, Ionela Avram, Sultana Nita, Adrian Vamanu, Study of PROBAC product influence on infant microbiota in a single-chamber colonic fermentation model GIS1, Annals of Microbiology – Spinger, vol. 63, issue 3, pp. 1029-1038, 2013, impact factor 1.549.

3. Emanuel Vamanu, Diana Pelinescu, Ionela Avram, Sultana Nita, An in-vitro evaluation of antioxidant and colonic microbial profile levels following mushroom consumption, BioMed Research International, Volume 2013, Article ID 289821, 2013, impact factor 2.88.

4. Emanuel Vamanu, Testing in vitro viability of a thermophilic probiotic bacterial strain in simulated gastrointestinal conditions, Annals of Microbiology – Springer, 64, 1439 – 1442, 2014, impact factor 1.039.

5. Emanuel Vamanu, Ionela Sarbu, Ioana Nedelcu, Diana Pelinescu, Study of PROEXO product influence on infant microbiota in an in vitro colonic fermentation system, Annals of Microbiology – Springer, 65, 2, 1189-1193, 2015, impact factor 1.039.

6. Emanuel Vamanu, Effect of gastric and small intestinal digestion on lactic acid bacteria activity in a GIS1 simulator, Saudi Journal of Biological Sciences (Elsevier) – accepted paper, 2015, impact factor 1.257.

7.  Veronica Ionela Moroeanu, Emanuel Vamanu, Gabriela Paun, Elena Neagu, Oana Rodica Ungureanu, Sandra V.A.M Eremia, Gabriel Lucian Radu, Robertina Ionescu, Diana Roxana Pelinescu, Probiotic strains influence on infant microbiota in the in vitro colonic fermentation model GIS1, Indian Journal of Microbiology (Springer) – 55, 4, 423-429, 2015, impact factor 0.899.

8. Emanuel Vamanu, Diana Pelinescu, Ionela Sarbu, Mihaela Ene, Influence of mushroom mycelia polyphenolic composition on human microbiota,  Free Radical Biology and Medicine – Elsevier, 2016, 96, S65,  impact factor 5.784.

9. Emanuel Vamanu, Diana Pelinescu, Ionela Sarbu, Comparative Fingerprinting of the Human Microbiota in Diabetes and Cardiovascular Disease, Journal of Medicinal Food, 19, 12, 1188-1195, 2016, impact factor 1.844.

10. Emanuel Vamanu, Diana Pelinescu, Ionela Avram (Sarbu), Antioxidative effects of phenolic compounds of mushrooms mycelia in simulated regions of the human colon, in vitro study, Polish Journal of Food and Nutrition Sciences, 68, 1, 2018, impact factor 0.679.

11. Emanuel Vamanu, Ionela Sarbu, Raluca Nita, Alexandra Andrada Mircea, 2017, IMPACT OF FOOD HABITS ON MICROBIOTA PROFILE OF HEALTHY ROMANIAN WOMEN, 7th Congress of European Microbiologists (Valencia, Spain, July 9 – 13, 2017).

12. Vamanu Emanuel, Pelinescu Diana, 2017, Effects of mushroom consumption on the microbiota of different target groups–Impact of polyphenolic composition and mitigation on the microbiome fingerprint, LWT-Food Science and Technology, 85, 262-268, factor de impact 2.329.

13. Vamanu Emanuel, Ionela Sarbu, 2017, In vitro prebiotic effect of mushroom extracts in order to mitigate of perturbed microbiome fingerprint, 5th World Congress on Targeting Microbiota, Berlin, Germany, October 26-27.

14. Vamanu, E.; Ene, M.; Biță, B.; Ionescu, C.; Crăciun, L.; Sârbu, I. In Vitro Human Microbiota Response to Exposure to Silver Nanoparticles Biosynthesized with Mushroom Extract. Nutrients 201810, 607, factor de impact 4.196.

15. Vamanu, E.; Gatea, F.; Sârbu, I. In Vitro Ecological Response of the Human Gut Microbiome to Bioactive Extracts from Edible Wild Mushrooms. Molecules 201823, 2128, factor de impact 3.098.

16. Vamanu E., Complementary functional strategy for modulation of human gut microbiota, Current Pharmaceutical Design. 2018, 24, 35, 4144-4149, factor de impact 2.757.

17. Vamanu E., Polyphenolic Nutraceuticals to Combat Oxidative Stress Through Microbiota Modulation. Frontiers in Pharmacology, 2019, 10, 492, factor de impact 3.845.

18. Vamanu, E., Gatea, F., Sârbu, I., Pelinescu, D. An In Vitro Study of the Influence of Curcuma longa Extracts on the Microbiota Modulation Process, In Patients with Hypertension. Pharmaceutics 201911, 191, factor de impact 4.773.

19. Vamanu, E.; Pelinescu, D.; Gatea, F.; Sârbu, I. Altered in Vitro Metabolomic Response of the Human Microbiota to Sweeteners. Genes 201910, 535, factor de impact 3.331.

20. Vamanu, E.; Gatea, F. Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-ReviewBiomedicines 20208, 39, impact factor 4.717.

21. Vamanu, E.; Gatea, F.; Pelinescu, D.R. Bioavailability and Bioactivities of Polyphenols Eco Extracts from Coffee Grounds after In Vitro DigestionFoods 20209, 1281, impact factor 4.092.

22. Dabulici, C.M.; Sârbu, I.; Vamanu, E. The Bioactive Potential of Functional Products and Bioavailability of Phenolic CompoundsFoods 20209, 953, impact factor 4.092.

23. Vamanu, E.; Dinu, L.D.; Pelinescu, D.R.; Gatea, F. Therapeutic Properties of Edible Mushrooms and Herbal Teas in Gut Microbiota Modulation. Microorganisms 2021, 9, 1262. (IF 4.128)

24. Vamanu, E.; Dinu, L.D.; Luntraru, C.M.; Suciu, A. In Vitro Coliform Resistance to Bioactive Compounds in Urinary Infection, Assessed in a Lab Catheterization Model. Appl. Sci. 2021, 11, 4315. (IF 2.679)

25. F Gatea, I Sârbu, E Vamanu In Vitro Modulatory Effect of Stevioside, as a Partial Sugar Replacer in Sweeteners, on Human Child Microbiota. Microorganisms 2021, 9, 590 – 2021 (IF 4.128)

26. …

Related papers:

1. Dabulici, C.M.; Sârbu, I.; Vamanu, E. The Bioactive Potential of Functional Products and Bioavailability of Phenolic Compounds. Foods 20209, 953. Impact factor – 4.092 (Q1 JCR)

2. Vamanu, E.; Rai, S.N. The Link between Obesity, Microbiota Dysbiosis, and Neurodegenerative Pathogenesis. Diseases 2021, 9, 45.

3. …



1. Patent 127801/2016 – GIS1 System:

  • Metoda de testare in vitro a viabilitații tulpinilor probiotice de bacterii lactice la tranzitul tractului gastrointestinal și sistem unicameral pentru aplicarea acesteia
  • Method for in vitro testing of the viability of lactic bacteria probiotic strains during gastrointestinal transit and unicameral system for its application

2. Patent 128300/2016 – GIS2 System:

  • Metodă de testare in vitro a viabilității tulpinilor probiotice la tranzitul prin colon și sistem pentru aplicarea metodei
  • A method of in vitro testing of the viability of the probiotic strains at the transit through the colon and system for method application
  • Procédé destiné au dépistage in vitro de la viabilité des souches probiotiques pendant le transit à travers le côlon et le système pour l’application du procédé

3. Patent 127731/28.02.2018

  • Procedeu de testare a viabilității bacteriilor lactice la tranzitul tractului gastrointestinal uman
  • Test procedure of the viability of lactic bacteria at the transit of the human gastrointestinal tract
  • Procédé pour tester la viabilité des bactéries lactiques au transit à travers du tractus gastro-intestinal humain

4. Patent request A/00407/2015 – GIS3 System:

  • Sistem semiautomat de testare in vitro a viabilității tulpinilor microbiene
  • In vitro semiautomatic system for testing the viability of microbial strains
  • In vitro système semi-automatique pour tester la viabilité de souches microbiennes

New projects:

– Update 1.0 to GIS1 system;

– Update 2.0 to GIS1 system.

ICM system